Taking hepabene. Gepabene - instructions for use of tablets, indications, composition, side effects, analogues and price

Many people face problems related to liver function. These can be chronic hepatitis, cholecystitis. With these diseases, the outflow of bile worsens, which leads to its stagnation and the development of liver failure. If you are often bothered by nausea and bitterness in your mouth, then you need to seek help from a therapist. This specialist will prescribe an ultrasound and computed tomography scan of the liver. Based on the results, the correct diagnosis will be made and professional treatment will be prescribed. The drug "Gepabene" has proven itself to be excellent. It is of plant origin, and many patients have gotten rid of existing health problems with its help.

Composition of Gepabene tablets

The drug has choleretic and hepatoprotective properties. The medicine has a herbal composition. Available in the form of gelatin capsules. The tablets are light brown in color. In the middle there is an orange powder. The drug consists of a dry extract of the fume herb, which contains protopine, and fruits in the form of a dry extract, containing silymarin.

Auxiliary components of the capsules are corn starch, macrogol, talc, microcrystalline cellulose. The capsule consists of gelatin, red iron oxide, black iron oxide, titanium dioxide and distilled water. Gepabene capsules have such a unique composition. Analogues of the drug will be presented below.

pharmachologic effect

"Gepabene" capsules have a combined composition. Fumarica officinalis extract contains the alkaloid fumarin. Thanks to this substance, spasm of the gallbladder and its ducts is relieved, bile penetrates more easily into the intestines. The amount of secretion produced also returns to normal.

Milk thistle fruit extract contains silymarin. It perfectly helps with intoxication. And most importantly, it promotes the appearance of new cells in the liver. Gepabene tablets help cope with various pathological processes in the liver. After entering the stomach, the medicine combines with bile and begins the process of breakdown in the liver and intestines. All information is contained in the packaging of Gepabene capsules. Instructions for use, price, reviews, analogues - all this can be studied before starting treatment.

Dosage of Gepabene capsules

The medicine has a very convenient release form. Gelatin capsules dissolve quickly in the stomach. It is recommended to take the product with meals. The contents of the capsule do not need to be poured out. You only need to drink the whole thing. You need to take the drug with plenty of water. Adults should take one tablet three times a day.

If pain bothers you at night, you should take another dose before going to bed. The maximum therapeutic dose should not exceed six capsules. The entire amount should be divided into three doses.

Many people are confused by the price of the medicine "Gepabene". Analogs of these capsules can be found much cheaper. For one package you will have to pay about 300 rubles.

Overdose

Until this time, medicine has not known cases of overdose. If signs of poisoning occur, you should immediately consult a doctor. When interacting with other dosage forms, the capsules do not lose their properties. It should be taken according to the indicated dosage of the Gepabene capsule. Analogues of the drug should also be used strictly according to the instructions.

Side effects

It is possible that when treated with Gepabene capsules, an allergic reaction may develop. In this case, you can additionally take antihistamines. In rare cases, urination may become more frequent. A suspicious symptom is diarrhea. If you feel unwell, you should immediately contact a specialist. The listed symptoms may indicate the development of hypersensitivity.

The medicine must be stored in a dry place, the air temperature should not exceed 25 degrees. You should definitely hide the drug from children. The implementation period for the funds is five years.

The medicine is of plant origin. In this regard, the drug "Gepabene" has very few side effects. Instructions for use, price, analogues - all this is important and necessary information for patients.

Indications and contraindications for the drug "Gepabene"

The medication is prescribed as a concomitant treatment for combination in the biliary tract. It can also be used for chronic forms of cholecystitis, for the treatment and prevention of various forms of hepatitis. Also, in case of severe poisoning and chronic toxic changes in the liver, capsules can be prescribed. All information about the correct use of Gepabene capsules (instructions for use, analogues, dosage) should be studied before starting treatment.

Do not take capsules for acute inflammatory conditions of the liver and biliary tract. Contraindication is age under 18 years. In rare cases, hypersensitivity to individual components may develop. During treatment with Gepabene capsules, patients should take only those medications prescribed by the doctor. Should be strictly observed special diet and regime, do not use alcoholic drinks.

Gepabene is an effective, fast-acting choleretic combination drug. The main active ingredients are dry plant extracts:
- fumerica officinalis
- fruits of milk thistle

What medicinal properties does the drug hepabene have, as described in its annotation? To find out about this, today we will get acquainted with this drug. However, when reading this text, please keep in mind that this information is not intended as a guide for use. Information based on official instructions, as well as based on medical experience and observations of patients taking hepabene. You can only get exact recommendations for your case from a doctor.

What is the composition of the drug Gepabene?

As we have already said, the product contains two main components:

Fumarin contains the alkaloid fumarin. This substance has choleretic and antispasmodic properties. It also normalizes the function of the liver to secrete bile, reduces the tone of the sphincter of Oddi, which makes bile easier to enter the intestines.

Milk thistle fruits contain a substance called silymarin. It has hepatoprotective properties. Silymarin binds toxins and free radicals found in liver tissue. It has antioxidant properties, activates protein synthesis and hepatocyte regeneration.

Thanks to this, the drug hepabene reduces the tone of the biliary tract, eliminates spasms of the gallbladder and ducts. The product normalizes the amount of bile secreted and its composition. It facilitates its outflow, while restoring hepatocytes.

Composition of capsules

The drug is presented in the form of capsules. Each contains 275.0 mg of fumitory (dry extract), from 70.0 to 100.0 mg of milk thistle fruit (dry extract). Except active substance each capsule contains auxiliary components: cellulose (microcrystalline), corn starch, talc, etc.

What are Gepabene's indications for use?

The drug is used in the complex treatment of biliary dyskinesia, in particular cholecystectomy. It is prescribed for complex therapy of chronic hepatitis. The drug is often prescribed in case of liver damage from toxins.

What are the uses and doses of Gepabene?

As the instructions say, the drug hepabene is taken with meals. Can be taken immediately after meals with liquid.

Adults are usually prescribed 1 capsule three times a day. In case of night pain, you can take another capsule before going to bed. If necessary, the doctor can increase the daily dose to 6 capsules. The duration of treatment is from 1 to 3 months.

Children are not treated with this drug.

During treatment with this drug, you need to change your diet. In particular, you should avoid fatty foods and avoid alcoholic beverages.

What is Gepabene's side effects?

Side effects are quite rare. Among them are nausea with possible vomiting, diarrhea, and frequent urination. Sometimes allergic manifestations are observed. If such negative reactions occur, you should stop taking the capsules and consult a doctor to replace the medicine with a more suitable one for you.

It should be noted that the drug does not cause drowsiness, so it can be used by people driving. There are no known cases of overdose with hepabene.

What are the contraindications for Gepabene?

Despite the natural, herbal composition of the drug, Gepabene’s instructions for use indicate that it has contraindications. In particular, this remedy should not be used in the presence of acute inflammation of the liver, as well as inflammatory diseases of the biliary tract.

Use during pregnancy

Pregnant women this remedy can be prescribed only when the need for its use to restore the health of the mother outweighs the possible risk of fetal development. The safety of using hepabene during breastfeeding has not been established.

In any case, this drug, like other pharmaceuticals, should be taken after the direct recommendation of the attending physician. Self-medication can cause harm to health instead of the desired recovery.

What are Gepabene's analogues?

The drug has no structural analogues, if we talk about the active substance, since its composition is unique. But in terms of the pharmacological group of hepatoprotectors, similar drugs are, in particular, drugs - simepar, uniliv, levasil, essentiale.

Last update of the description by the manufacturer 09/30/2016

Filterable list

Active substance:

ATX

Pharmacological groups

3D images

Compound

Description of the dosage form

Hard gelatin capsules, size 0, light brown. The contents of the capsules are a powder from orange-brown to light brown in color, with lighter inclusions.

pharmachologic effect

Pharmacodynamics

Gepabene ® is a combination preparation of plant origin, containing fumaria officinalis extract and milk thistle extract.

Fumarica officinalis extract, containing the alkaloid fumarin, normalizes the amount of secreted bile, relieves spasm of the gallbladder and bile ducts, facilitating the flow of bile into the intestines.

Milk thistle fruit extract contains silymarin, which exhibits a hepatoprotective effect in acute and chronic intoxication, binds free radicals and toxic substances in liver tissue, has antioxidant and membrane-stabilizing activity, stimulates protein synthesis, and promotes the restoration of liver cells.

Gepabene ® normalizes liver function in various chronic pathological conditions.

Pharmacokinetics

After oral administration, the flavonoids that make up silymarin are excreted mainly in bile and undergo enterohepatic recirculation.

Indications for the drug Gepabene

As part of complex therapy:

biliary dyskinesia, incl.

after cholecystectomy;

chronic hepatitis;

chronic toxic liver damage.

increased individual sensitivity to the components of the drug;

spicy inflammatory diseases liver and biliary tract;

children under 18 years of age.

Use during pregnancy and breastfeeding

The use of the drug during pregnancy and breastfeeding is possible only as prescribed by the attending physician.

Side effects

Allergic reactions are possible.

Sometimes a laxative effect and increased diuresis may occur.

Interaction

Not described to date.

Directions for use and doses

Gepabene is a hepatoprotector, a choleretic drug based on components of plant origin.

Release form and composition

Gepabene is produced in hard, gelatinous, light brown capsules. The contents of the capsules are powder, the color of which varies from orange-brown to light brown, with light inclusions.

The active ingredients of the drug are the following herbal components:

• Dry extract of the herb fumaria officinalis 275.1 mg (including protopin 4.13 mg);
• Dry extract of milk thistle fruits 83.1 mg (including silymarin 50 mg, silibinin 22 mg).

The auxiliary components of the drug are: corn starch, microcrystalline cellulose, silicon dioxide, magnesium stearate, talc, macrogol 6000, copolyvidone, titanium dioxide, purified water, gelatin, black iron oxide, red iron oxide, yellow iron oxide.

There are 10 capsules in blisters, 3 blisters in cardboard packages.

Indications for use

According to the instructions, Gepabene is indicated for use as part of the complex treatment of the following diseases:

• Chronic hepatitis (including chronic persistent, subacute and chronic active forms);
• Biliary dyskinesia, including after cholecystectomy (surgical intervention to remove the gallbladder);
• Liver cirrhosis;
• Fatty liver degeneration;
• Toxic-metabolic liver damage, including xenobiotics;
• Chronic toxic liver damage.

chronic toxic liver damage.

According to the instructions, Gepabene should not be used in the following cases:

• Hypersensitivity to the active or auxiliary components of the herbal medicine, as well as to other plants of the Asteraceae family;
• Acute poisoning of various types;
• Cholelithiasis;
• Cholangitis or acute hepatitis;
• Acute inflammatory diseases of the liver and biliary tract;
• Obstruction of the biliary tract.

Directions for use and dosage

The herbal medicine Gepabene is intended for internal use. Capsules are taken after meals and washed down with half a glass of water. The standard dosage of the drug is 1 capsule three times a day.

If the patient experiences pain at night, additional use of Gepabene before bed in the amount of 1 capsule is recommended.

The daily dose of the drug, at the discretion of the attending physician, can be increased to 6 capsules, divided into several doses. The duration of therapy is determined by the attending physician individually, and depends on the type of disease, the severity of its course and the effectiveness of therapy.

Elderly patients do not require dose adjustment.

Side effects

The use of Gepabene is generally well tolerated by patients. If the recommended dosage is followed, the herbal medicine does not cause side effects. In rare cases, the following negative reactions from various vital systems of the body cannot be ruled out:

• Digestive system: nausea, vomiting, diarrhea, dyspepsia, heartburn;
• Urinary system: increased diuresis;
• Skin and subcutaneous tissue: alopecia (baldness);
• Cardiovascular system: sudden feeling of heat in the face and upper part of the body;
• Vestibular system: dizziness, sweating, changes in blood pressure, loss of balance, loss of coordination of movement.

In addition to the above side effects, Gepabene can cause the development of allergic reactions in the form of urticaria, rashes, itching on the skin due to hypersensitivity to the components of the drug.

special instructions

Gepabene capsules contain silymarin, which can have an estrogen-like effect, so the phytotherapeutic drug is recommended to be used with caution in patients with hormonal imbalances and diseases such as carcinoma of the prostate, ovaries, uterus, breast, uterine fibroids, endometriosis, etc.

If Gepabene is used in excessive dosages, it is theoretically possible to develop abdominal pain and diarrhea. In this case, the patient should stop taking the drug and consult a doctor.

Due to inhibition of the cytochrome P450 system, Gepabene is able to enhance the effect medicines containing vinblastine, diazepam, lovastatin, clopidogrel, warfarin, ketoconazole, alprazolam, fexofenadine.

Women taking estrogen replacement therapy or oral contraceptives should be aware that silymarin, which is part of Gepabene, may reduce the effectiveness of these drugs.

Analogs

Based on the similarity of the mechanisms of action and belonging to the same pharmacological group, the following can be classified as analogues of Gepabene: medications: Arnica tincture, Allohol, Artichol, Artichoke extract, Artibel, Berberine, Artichoke Sandoz, Barberry leaves tincture, Immortelle sandy flowers, Tanacehol, Tansy flowers, Salvat, Hepatcinar, Corn columns with stigmas, Convaflavin, Holos, Holosas, Liobil, Rosehip low-vitamin fruits, Holagol, Olimetin, Odeston, Choleretic collection No. 2, Gepatsinar, Bonjigar, Hofitol, Cynarix, Rafacholin C, Holemaks, Flamin, Tsikvalon.

One capsule contains dry plant extracts: 275.10 mg medicinal fume herbs and 83.10 mg spotted milk thistle fruit .

Additionally: colloidal silicon dioxide, macrogol, microcrystalline cellulose, copovidone, talc, corn starch, magnesium stearate, titanium dioxide, gelatin, iron oxide (yellow, red, black).

Release form

The medicine Gepabene is produced in the form of hard capsules No. 30.

pharmachologic effect

Hepatoprotective, choleretic.

Pharmacodynamics and pharmacokinetics

Gepabene is a herbal combination remedy that includes extracts of fumifera And milk thistle , due to which the medicinal effects of the drug are manifested, used in medicine to normalize liver function in its various pathological conditions.

Application pharmaceutical smoker containing alkaloid fumarin , helps normalize the volume of secreted fluid, facilitating its flow to the intestines, relieves spasms bile ducts and gallbladder.

Included in milk thistle , is characterized by a hepatoprotective effect, manifested in chronic and acute liver diseases (by binding toxic substances and free radicals in the liver tissue), stimulates protein synthesis , has membrane stabilizing and effectiveness, favors the restoration of damaged liver cells.

When taken orally silymarin flavonoids pass through the stage of enterohepatic recirculation and are predominantly excreted from the body with bile.

Indications for use

Gepabene capsules are indicated for the treatment of:

• chronic toxic ;
• chronic ;
• (including conditions after a previous cholecystectomy ) together with other medicinal drugs used in such cases.

chronic toxic liver damage.

The medicine Gepabene is contraindicated in children under 18 years of age, patients with personal hypersensitivity to the ingredients of the capsules, as well as patients with acute inflammatory pathologies of the biliary tract and liver.

Side effects

In some cases, when taking capsules, an increase in , laxative effect and various manifestations .

Gepabene, instructions for use (Method and dosage)

The course of treatment is determined individually. Instructions for use of Gepabene involve taking capsules of the medicinal product together with food in its entirety (do not chew or crush the capsules), washing down with the required amount of water.

Adult patients are usually recommended to take 3 capsules per day, at relatively equal intervals. In case of manifestation night pain syndrome allow taking an additional capsule immediately before bedtime. It is possible to increase the daily dosage of the drug to 6 capsules (this dose is the maximum), taken 3-4 times over 24 hours.

Overdose

Until today, no negative effects from an overdose of Gepabene capsules have been observed. If a large number of capsules are inadvertently taken, the patient should consult their physician.

Interaction

The interaction of the active ingredients of the drug with other medicinal products has not been described.

Terms of sale

Upon presentation of a prescription.

Storage conditions

Capsules retain their medicinal properties at temperatures up to 25 °C.

Best before date

5 years from the date of production.

special instructions

During the therapeutic course, patients must take only the medications prescribed by the doctor, follow the regimen for taking them, and strictly adhere to the prescribed diets .

Gepabene's analogs

Analogues of the drug Gepabene include medicinal products, most often plant origin (tablets, preparations, syrups, tinctures) used for such liver pathologies.